Patented Skincare Technologies

JRX is a specialty biotechnology company. We are also a contract R&D laboratory focused on formulating cosmetic topical products. We combine our patented bio-technologies with formulation expertise to address large, unmet White Space market needs in the personal care and skincare industries.
JRX is different. We are the owners, developers and patent holders of the following two distinct proprietary topical technology platforms, listed below.

DermX® Megasphere® Delivery System

enhanced skin penetration

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DermX® is a topical, passive dermal / transdermal delivery system technology. It is a mixture of excipients formulated in a precise way that enhance the volume, depth and speed of delivery of small and large active ingredients into and through the skin.
What’s Different? The ability to deliver large volumes of small or large molecules into the skin that translates to a consumer-meaningful result. We call it User Impact. For example, a DermX-powered skincare product has been clinically proven at an independent testing laboratory to push into the skin a 2-Million Dalton molecule that resulted in compelling Before/After images and an increase in the thickness of the Dermal-Epidermal Junction (DEJ) (measured in-vivo, n=26, p≤0.05).
Intellectual Property: Patented and patent pending.
Benefits in Finished Products: An increase in skin absorption translates to:

• Enhanced efficacy

DermX-powered cosmetic products have been independently, clinically proven to work double the anti-wrinkle / fine line effect vs. peer products (p≤0.05).

• Accelerated results

DermX-powered cosmetic products have been independently, clinically proven to achieve results in 15 minutes (hydration), 1 day (fine lines, roughness, radiance), and 1 week (results along 11 clinically measured dimensions) (all p≤0.05).

• Increased bioavailability of active ingredients

DermX-powered cosmetic products have been independently, clinically proven to perform more effectively than industry standard prescription (Rx) products (p≤0.05).

Market Validation: Out-licensed to and commercialized by a number of skincare brands, including online, mass retail, celebrity, prestige retail, physician-dispensed brands as well as a billion-dollar dermatology company and North America’s leading pharmacy supplier.
Consumer Adoption: DermX® has been sold – collectively – in over 100 million skincare units and can be found in over 42 countries.
For More Information: Email us at DermX@jrxbiotech.com

HydrO18® Activated Water®

enhanced skin hydration

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HydrO18® is a new kind of clean, “activated” water designed specifically for a topical consumer. It is used to replace the standard, unscientific deionized or purified water extensively used in personal, skin and haircare products (for example: serums, lotions, creams, shampoos).
HydrO18® makes water more valuable to brands and more meaningful to the consumer.
Problem – Defined: Water is – by far – the #1 volume ingredient used throughout the topical cosmetic industry. That’s because it is readily available, not very expensive, and benefits the formula (it helps dissolve active ingredients into liquid or the term of art is: “solubilized”). But yet: it does nothing for the skin. By definition water and skin are incompatible. It doesn’t even hydrate our skin. This is why we don’t drown when we shower or swim.
Using so much of something – every day – that does nothing for you created a disconnect we sought to find a solution for.
Solution – Developed: We solve the problem with HydrO18® Activated Water®. Our new, clean water is bio-compatible with the skin and feeds it with nutrients. The lipid profile of our water mimics the lipid profile of healthy skin. Our water still solubilizes active ingredients (like traditional water), but was thoughtfully built with the skin in mind.
Time for an Upgrade: As biochemists, we aren’t sure why topical consumers tolerate using so much of an ingredient – water – that does nothing for their skin. It’s inactive, boring and low-tech, or really: no-tech. Did you know that a skincare product can be made with as much as 80% water? It’s true. Read the back label on your favorite body lotion, sunscreen or shampoo bottle. You will note that “Water” or “Aqua” [or “Water (Aqua)”] is the very first ingredient listed (if listed legally and correctly). That means water represents the single highest concentration ingredient used in the formula.
In other words, 80% of certain formulas do nothing to benefit you. And you’re paying good money for these products! Isn’t there a better way? We think so. That’s why we have created, with the consumer in mind, a topical water specifically designed to benefit the skin.
Intellectual Property: Patented and patent pending.
Features & Benefits in Finished Products: HydrO18® makes water an active ingredient within your favorite formula and has the following features and benefits:

• Skin Hydration

clinically proven* to hydrate skin by 36% (15 mins) and 41% (8 hours) after one application (p≤0.05).

(*7 studies on over 70 human subjects with over 500 skin site Corneometer/ Novameter readings across 3 different independent test sites at various times of the year)

• Skin Health

feeds the skin with nutrients and Omegas 3, 6 & 9 fatty acids (lipids found in healthy human skin).

• More Sustainable

reduces your water footprint vs. traditional water used in today’s topical products.

• Nature Water

our water is sourced from plants, trees and seeds -- nature. Did you know that the water used in your favorite lotion or shampoo is sourced from local city water?

• Wellness Water

we react our water with an emollient. This means you can now actually feel our water being applied while it leaves the skin feeling soft and smooth after application.

• Clean Water

our water qualifies as a “Clean” ingredient as defined by Sephora**.

(**Sephora Clean means no: sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, and triclocarban – posted online as of 22-Aug-2018)

• Timely

a new kind of designer water for a new kind of extraordinarily informed and well-educated topical consumer that, quite frankly, deserves better.

• New Claims

now water is an active ingredient in your favorite lotion or shampoo. Therefore, you can claim (for example) that “80%” or more of your formula contains active ingredients. Or, you (for example) have “8X” the active ingredients vs. a non-HydrO18 formula.

Doesn’t more = better?

• New Story

our Activated Water® is new. This “Wellness Water” or “Green Water” is designed specifically for a topical consumer and is clinically proven and patented to hydrate skin and reduce your water footprint. And this is science. We lipidize the water. Which means we react into our water the same exact lipids found in healthy, human skin.

Market Validation: Out-licensed to a number of contract manufacturing organizations (CMOs) and commercialized by one skincare brand, with several more brands coming to market soon with other HydrO18-powered formulas.
Consumer Adoption: HydrO18® Activated Water® is new and first introduced to the market in June 2018.
For More Information: Email us at HydrO18@jrxbiotech.com

Team

JRX is made up of a collection of entrepreneurs, industry executives and advisors. The founding team has a track record of starting, financing and building companies based on bringing innovative technologies to market. Our board member was the former Global President / CEO of Neutrogena, former CEO of philosophy, and then became Executive Chairman of Too Faced Cosmetics before it was sold to Estée Lauder. Our lead skincare consultant was the former Global Vice President of R&D at Mary Kay, and then was a senior technical advisor (1 of 2) to La Prairie. We also have a team of well-known advisors / consultants with significant experience in passive skin penetration, surface chemistry and raw material science.

Working with JRX

Contract topical formulation work, out-licensing, partnerships, collaborations and co-development agreements are at the heart of what we do.
If you are interested in:

• Technology

licensing our technologies, or

• Products

accessing finished formulations and prototypes that incorporate our technologies, or

• Performance

need proprietary skin penetration or skin hydration technology that fills an unmet need or consumer White Space, then

Please contact us here.

Contact Us

Headquarters and Full-Service Technology R&D Lab:

1401 Quail Street
Suite 115
Newport Beach, CA 92660
Phone: (949) 748-8863